《Myelodysplastic Syndromes MDS》专家PPT内容预览
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《Myelodysplastic Syndromes MDS》专家PPT内容简介
Myelodysplastic Syndromes Between FAB and WHO
Mona F. Melhem, MD
Professor, Department of Pathology
University of Pittsburgh School of Medicine
Chief Hematology
VA Medical Center of Pittsburgh
Pittsburgh, Pennsylvania

Myelodysplastic Syndromes (MDS)
Clonal hematopoietic Stem Cell Disease
Dysplasia
Ineffective Hematopoiesis (1 or more lines)
Myeloblasts < 20% of all marrow cells
Synonyms:
Dysmyelopoietic syndromes
Preleukemic syndromes
Oligoblastic leukemia

MDS: Epidemiology
Older adults (median age: 70 years)
Primary vs. Secondary MDS (S/P chemotherapy)
Incidence: 3/100,000 non-age corrected
20/100,000 over age 70

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