《Management of Babies Born to HBsAg- Positive Mothers》专家PPT内容预览
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《Management of Babies Born to HBsAg- Positive Mothers》专家PPT内容简介
About Hepatitis B Infection
Spread by:
Sexual
Parenteral
Perinatal
Acute and/or Chronic
Chronic infection is a leading cause of liver disease.

Hepatitis B – Clinical Features
Acute
New infection
Symptoms more common among adults
Children often asymptomatic.
Two possible outcomes:
Infection resolves: person develops immunity
infection does not resolve and the person continues to carry the virus
Chronic
Individual carries the virus for >6 months and does not develop anti-bodies to the surface antigen (anti-HBsAg)
Silent infection
People that become infected as children are more likely to become chronically infected.

HBV Testing
HBsAg:
(hepatitis B surface antigen)
Marker of current infection
Neutralization
HBsAb:
(hepatitis B surface antibody)
Marker of immunity
HBeAg:
(hepatitis B e antigen)
Marker of high infectivity
Anti-HBe
(hepatitis B e antibody)
Marker of low infectivity
Anti-HBc IgM
(hepatitis B core antibody IgM)
If +, acute infection
if negative and HBsAg +, chronic infection
Anti-HBc
(hepatitis B core antibody)
Marker of current or previous infection

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